Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats. Hypertension ; 32 : — Expression of angiotensin II AT2 receptor in the acute phase of stroke in rats. Neuroreport ; 11 : — Human skin: source of and target organ for angiotensin II. Exp Dermatol ; 13 : — Differential expression angiotensin receptors in human cutaneous wound healing.
Br J Dermatol ; : — Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries. Circulation ; : — Tissue-specific expression of human angiotensin II AT1 and AT2 receptors and cellular localization of subtype mRNAs in adult human renal cortex using in situ hybridization. Nephron ; 80 : 25— Contribution of angiotensin II internalization to intrarenal angiotensin II levels in rats.
Guyton AC ed. Human Physiology and Mechanisms of Disease , 5th edn. Lumbers ER. Angiotensin and aldosterone. Regul pept ; 80 : 91— Hall JE. Control of sodium excretion by angiotensin II: intrarenal mechanisms and blood pressure regulation.
Angiotensin II receptor signaling. Exp Physiol ; 92 : — Differential effect of angiotensin II on blood circulation in the renal medulla and cortex of anaesthetised rats. J Physiol ; : — Responses to angiotensin peptides are mediated by AT1 receptors in the rat.
AT1 receptor-activated signaling mediates angiotensin IV-induced renal cortical vasoconstriction in rats. Regional renal haemodynamics of angiotensin II infusion under prostaglandin, kinin or converting enzyme inhibition in the Wistar rat. Blood Press ; 9 : — Cardiovascular phenotype of mice lacking all three subtypes of angiotensin II receptors. Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated.
J Hypertens ; 28 : — Regulation of blood pressure by the type 1A angiotensin II receptor gene. Angiotensin II type 1a receptor-deficient mice with hypotension and hyperreninemia. J Biol Chem ; : — Targeting deletion of angiotensin type 1B receptor gene in the mouse.
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes. J Clin Invest ; : — Shanmugam S, Sandberg K. Ontogeny of angiotensin II receptors. Cell Biol Int ; 20 : — Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
Effects of truncated angiotensins in humans after double blockade of the renin system. Paulis L, Unger T. Novel therapeutic targets for hypertension. Nat Rev Cardiol ; 7 : — Huang WC. Chin J Physiol ; 34 : — Angiotensin II: enhanced renal responsiveness in young genetically hypertensive rats.
J Pharmacol Exp Ther ; : — Handa RK. Biphasic actions of angiotensin IV on renal blood flow in the rat. Regul Pept ; : 23— Autoradiographic identification of kidney angiotensin IV binding sites and angiotensin IV-induced renal cortical blood flow changes in rats. Peptides ; 19 : — Effects of prostaglandins and nitric oxide on the renal effects of angiotensin II in the anaesthetized rat. Br J Pharmacol ; : — Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat.
J Hypertens ; 26 : — Actions of angiotensin II on the renal microvasculature. In vivo visualization of angiotensin II- and tubuloglomerular feedback-mediated renal vasoconstriction. Mechanisms of angiotensin II natriuresis and antinatriuresis.
Volume natriuresis vs. Acta Physiol Scand ; : — Mechanisms of pressure natriuresis. Curr Hypertens Rep ; 4 : — Intrarenal mechanisms mediating pressure natriuresis: role of angiotensin and prostaglandins.
Fed Proc ; 45 : — Zhao D, Navar LG. Acute angiotensin II infusions elicit pressure natriuresis in mice and reduce distal fractional sodium reabsorption.
Hypertension ; 52 : — Harris PJ. Stimulation of proximal tubular sodium reabsorption by ile5 angiotensin II in the rat kidney. Pflugers Arch ; : 83— Kidney Int ; 50 : — Intrarenal effects of the renin—angiotensin system. Fed Proc ; 38 : — Biphasic effect of angiotensin II on intracellular sodium concentration in rat proximal tubules.
Burns KD, Li N. The role of angiotensin II-stimulated renal tubular transport in hypertension. Curr Hypertens Rep ; 5 : — Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice.
Nature ; : — Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function.
Hypertension ; 35 : — Expression and role of angiotensin II type 2 receptor in the kidney and mesangial cells of spontaneously hypertensive rats. Hypertens Res ; 25 : — Angiotensin AT2 receptors: control of renal sodium excretion and blood pressure.
Trends Endocrinol Metab ; 19 : 84— Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients.
Hypertension ; 49 : — The subtype 2 angiotensin receptor regulates renal prostaglandin F-2 alpha formation in conscious rats. Am J Physiol ; 42 : R—R Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 AT2 angiotensin receptor.
Increased renal vasodilator prostanoids prevent hypertension in mice lacking the angiotensin subtype-2 receptor. Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases.
Angiotensin type 2 receptor-mediated hypotension in angiotensin type-1 receptor-blocked rats. Hypertension ; 38 : — Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. J Med Chem ; 47 : — Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats.
Renal proximal tubular AT2 receptor: signaling and transport. Inhibition of pressure natriuresis in mice lacking the AT2 receptor. Kidney Int ; 57 : — Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat.
Hypertension ; 47 : — Nitric oxide in responses of regional kidney blood flow to vasoactive agents in anesthetized rabbits. J Cardiovasc Pharmacol ; 40 : — Bergstrom G, Evans RG. Mechanisms underlying the antihypertensive functions of the renal medulla. Angiotensin II and renal medullary blood flow in Lyon rats.
Liu KL. Regulation of renal medullary circulation by the renin—angiotensin system in genetically hypertensive rats. Clin Exp Pharmacol Physiol ; 36 : — Angiotensin III: a central regulator of vasopressin release and blood pressure.
Trends Endocrinol Metab ; 12 : — Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release. Angiotensin IV is a potent agonist for constitutive active human AT1 receptors. Biological properties of the angiotensin peptides other than angiotensin II: implications for hypertension and cardiovascular diseases.
J Hypertens ; 20 : — Effects of angiotensin on renal cortical and papillary blood flows measured by Laser-Doppler flowmetry. Systemic effects of angiotensin III in conscious dogs during acute double blockade of the renin—angiotensin—aldosterone-system. Acta Physiol Oxf ; : — Effects of des-aspartate-angiotensin I on the actions of angiotensin III in the renal and mesenteric vasculature of normo- and hypertensive rats. Regul Pept ; : 15— Healy DP, Song L. Kidney aminopeptidase A and hypertension, part I: spontaneously hypertensive rats.
Hypertension ; 33 : — Intrarenal aminopeptidase N inhibition augments natriuretic responses to angiotensin III in angiotensin type 1 receptor-blocked rats. Reversal by angiotensins II and III of the effects of converting enzyme inhibition on renal electrolyte excretion in rats.
Hypertension ; 1 : 95— Renal and adrenal responses to [des. Asp[1]1] angiotensin I in the dog. Effects of different angiotensins during acute, double blockade of the renin system in conscious dogs. Ardaillou R, Chansel D. Synthesis and effects of active fragments of angiotensin II.
Kidney Int ; 52 : — Characterization of angiotensin IV-degrading enzymes and receptors on rat mesangial cells. Eur J Pharmacol ; : — Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells. Aminopeptidase A inhibitors as potential central antihypertensive agents. Characterization and function of the bovine kidney epithelial angiotensin receptor subtype 4 using angiotensin IV and divalinal angiotensin IV as receptor ligands.
Discovery of a distinct binding-site for angiotensin-II , a putative angiotensin-IV receptor. Regul Pept ; 40 : — Structural analysis of angiotensin IV receptor AT4 from selected bovine tissues.
Evidence that the angiotensin IV AT 4 receptor is the enzyme insulin-regulated aminopeptidase. Angiotensin IV receptors and signaling in opossum kidney cells. Hemorphins inhibit angiotensin IV binding and interact with aminopeptidase N.
Evidence for angiotensin IV receptors in human collecting duct cells. Characterization and signaling of the AT 4 receptor in human proximal tubule epithelial HK-2 cells. J Am Soc Nephrol ; 12 : — Central angiotensin-IV binding-sites—distribution and specificity in Guinea-Pig brain. Distribution of angiotensin IV binding sites AT4 receptor in the human forebrain, midbrain and pons as visualised by in vitro receptor autoradiography.
J Chem Neuroanat ; 20 : — J Intern Med ; : — Peptides ; 22 : — Angiotensin IV receptor-mediated activation of lung endothelial NOS is associated with vasorelaxation. Am J Physiol ; : L—L Role of nitric oxide in angiotensin IV-induced increases in cerebral blood flow. Regul Pept ; 74 : — Modulation by nitric oxide and prostaglandin of the renal vascular response to angiotensin II 3—8. Regional haemodynamic effects of angiotensin II 3—8 in conscious rats. Renal hemodynamic responses to intrarenal infusion of ligands for the putative angiotensin IV receptor in anesthetized rats.
J Cardiovasc Pharmacol ; 34 : — Endogenous cystinyl aminopeptidase in Chinese hamster ovary cells: characterization by [ I]Ang IV binding and catalytic activity. Biochem Pharmacol ; 68 : — The renal circulation. The Kidney. Renal microvascular actions of angiotensin II fragments. A novel angiotensin-converting enzyme-related carboxypeptidase ACE2 converts angiotensin I to angiotensin 1—9.
Circ Res ; 87 : E1—E9. Metabolism of angiotensin 1—7 by angiotensin converting enzyme. Hypertension ; 31 : — Angiotensin- 1—7 is an endogenous ligand for the G protein-coupled receptor Mas. Angiotensin- 1—7 acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats.
Evidence for a physiological role of angiotensin- 1—7 in the control of hydroelectrolyte balance. Hypertension ; 27 : — Regulation of cardiovascular signaling by kinins and products of similar converting enzyme systems—systemic and regional hemodynamic effects of angiotensin- 1—7 in rats. Characterization of angiotensin- 1—7 in the urine of normal and essential hypertensive subjects. Am J Hypertens ; 11 : — Effects of angiotensin 1—7 on the actions of angiotensin II in the renal and mesenteric vasculature of hypertensive and streptozotocin-induced diabetic rats.
Angiotensin 1—7 in the spontaneously hypertensive rat. Peptides ; 14 : — The role of angiotensin 1—7 in renal vasculature of the rat. J Hypertens ; 24 : — Renal actions of angiotensin- 1—7 : in vivo and in vitro studies. Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides.
Hypertension ; 23 : — Renal actions of angiotensin- 1—7. Braz J Med Biol Res ; 30 : — Vasodilator action of angiotensin- 1—7 on isolated rabbit afferent arterioles. Hypertension ; 39 : — Effect of intrarenal infusion of angiotensin- 1—7 in the dog.
Kidney Blood Press Res ; 23 : 89— Biological activities of angiotensin II 1—6 hexapeptide and angiotensin II 1—7 heptapeptide in man. Life Sci ; 38 : — Effect of angiotensin 1—7 and bradykinin in patients with heart failure treated with an ACE inhibitor. Hypertension ; 34 : — Pressor and renal effects of angiotensin A [abstract]. J Hypertens ; 27 : S Analysis of hemodynamic responses and the proliferative effect of the novel angiotensin peptide Angiotensin A.
Angiotensin II receptors in adrenal cortex and uterus. To combat these adverse effects, drugs such as angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are used in the clinic, although these do have side effects and can lead to excessive retention of potassium hyperkalaemia. Control of plasma sodium and potassium concentrations, and the regulation of blood volume and pressure, are all hormonal mechanisms that are impaired by low angiotensin levels.
Absence of angiotensin can be associated with retention of potassium, loss of sodium, decreased fluid retention increased urine output and low blood pressure. About Contact Events News. Search Search. You and Your Hormones. Students Teachers Patients Browse. Human body. Home Hormones Angiotensin. Angiotensin Angiotensin is a protein hormone that causes blood vessels to become narrower.
It helps to maintain blood pressure and fluid balance in the body. Alternative names for angiotensin The different forms of angiotensin are denoted by Roman numerals, angiotensin I—IV. What is angiotensin? Angiotensin II has effects on: Blood vessels — it increases blood pressure by causing constriction narrowing of the blood vessels Nerves: it increases the sensation of thirst, the desire for salt, encourages the release of other hormones that are involved in fluid retention.
How is angiotensin controlled? What happens if I have too much angiotensin? What happens if I have too little angiotensin?
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